ChOX
ChOX (short for Chemical Object Explorer) is a handy GUI tool for browsing the contents of chemical structure and reaction data files.
Key Features
Can handle large files containing millions of molecules/reactions without memory or performance issues
Performs 2D structure layout on-the-fly if required/desired
A large array of structure/reaction visualization settings
Allows the selection of individual entries for file export or printing
A wide panel of supported input and output file formats
Can perform SMARTS-based substructure searching supporting the combination of multiple SMARTS patterns via logical operators
Provides functionality for substructure highlighting
Display of molecule and reaction data in tabular form

ChOX displaying the contents of an SD-file.